Thyroid function instrument

Overview

HH6008 thyroid function instrument is my company development and mass production of products, the instrument through the human thyroid iodine absorption rate, inhibition rate, half-time and potassium perchlorate release rate and other test indicators of the determination of thyroid disease diagnosis.

Main product structure:

instrumentGamma probe and its support, interface circuit, computer control several parts. The probe bracket is of floor structure, beautiful appearance, convenient and practical. The control and data processing of the measurement process are completed by a high-performance computer system.

Product performance indicators:

1. The background count shall not be greater than 900 m/min.

2. Point source sensitivity is not less than 0.25/min.bq for 131I and 0.20/(min.bq) for 137Cs

8 hours working stability: the counting rate error is less than 5%;

4. The thyroid iodine absorption rate, inhibition rate, effective half-period and potassium perchlorate release rate can be measured, the measurement results of the corresponding data processing and display print measurement curves and indicators.

A Brief Introduction of the Nail Gone Instrument and Its Clinical Application

A work meterA device used to measure the function of the thyroid gland.

Iodine is the main raw material of thyroid synthesis of thyroxine, so131I(NA131I) can be ingested and concentrated by the thyroid gland, giving patients

ClothingNA131I solution or capsule, and the gamma rays emitted by 131I were measured at the thyroid site with a thyroid instrument. According to the measured quantity

and its dynamic changes to determine the functional status of the thyroid gland. This method we call iodine uptake measurement.

The nail work meter is checked by measuring the iodine absorption rate, and the doctor can judge the data according to the normal value. If diagnosisIf the test is not clear, the inhibition test of thyroid hormone and the release test of perchlorate can be carried out for further diagnosis.

Under normal conditions, thyroid uptakeThe 131I rate is regulated by TSH secreted by the anterior pituitary. After oral administration of thyroid hormone T3 or T4, the concentration of T3 and T4 in blood increases. Through negative feedback, the secretion of TSH in anterior pituitary decreases, and the uptake rate of 131I in thyroid gland decreases significantly, which is called obvious inhibition. Hyperthyroidism makes this feedback regulation completely or partially disappear, and there is no significant decrease in thyroid iodine absorption rate after oral administration of T3 or T4, which is called no obvious inhibition. This experiment has good specificity for the diagnosis of hyperthyroidism

Perchlorate Release Test:

Perchlorate has the effect of preventing the thyroid gland from taking iodine ions from the blood and promoting the release of iodine ions from the thyroid gland. The iodine ion ingested by the normal thyroid gland is rapidly converted into organic iodine under the action of enzymes, so there is no problem of iodine ion being released by perchlorate. However, when the iodine ion is in organic disorder, the iodine ion ingested in the thyroid gland can be released by perchlorate, which can assist in the diagnosis of diseases related to the iodine organic disorder in the thyroid gland.(typically manifested as a low).

Testing in the bloodT3, T4, TSH to determine the function of thyroid gland, one-time detection can also, if monitoring the situation during treatment,Multiple sampling is inconvenient. In the diagnosis of the use of a work instrument has its very big advantages, in the treatment, a work instrument monitoring is also very important. 

Use131I treatment of hyperthyroidism, functionally autonomous thyroid tumor, thyroid cancer metastasis, malignant pheochromocytoma, sympathetic neuroblastoma and other diseases is one of the effective treatment methods widely used in the world. Including U.S. President Reagan suffering from hyperthyroidism, this method is also used for treatment. Thyroid gland has the function of highly selective uptake of 131I, and the uptake of hyperactive thyroid gland will increase. During the effective half-decrement period (about 3-5 days) of 131I in hyperthyroid patients, 131I decay releases a large amount of β particles, which will partially inhibit or destroy hyperactive thyroid tissue to achieve the purpose of treating hyperthyroidism. And these particles have a short range, only 2~3mm, and generally have no effect on normal surrounding tissues, so this method is one of the effective methods for the treatment of hyperthyroidism. The principle of the other three treatment methods is the same and will not be described again.